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Baltimore Orioles, Cleveland Guardians

CBS Sports on MSN · 8h

Orioles vs. Guardians odds, line, prediction, time: 2025 MLB picks, best bets for July 22 by proven model

SportsLine's model simulated Baltimore Orioles vs. Cleveland Guardians 10,000 times and revealed its MLB picks for Tuesday's matchup at Progressive Field in Cleveland

NBC Sports on MSN · 5h

Orioles at Guardians Prediction: Odds, expert picks, starting pitchers, betting trends and stats for July 22

The Guardians took the first game of the series, 10-5, behind a four-run sixth inning. Cleveland is 3-1 since the break and has scored 28 runs. Baltimore is 1-3 post-break and totaled 14 runs in that span with 10 coming in the past two games.

FOX Sports · 23h

Guardians vs. Orioles Prediction, Odds, Picks - July 22

Preview the July 22 matchup between the Cleveland Guardians and Baltimore Orioles with odds over/under, game spread, betting lines and more.

3 home runs power Guardians to 10-5 victory over Orioles

cleveland.com on MSN · 17h

Three home runs power Guardians to 10-5 victory over Orioles; José Ramírez secures historic 20/20 season

José Ramírez, Bo Naylor and Kyle Manzardo go deep as the Guardians extend their streak to 11 straight games with a home run.

The Southern Maryland Chronicl… · 1h

Ramírez's Homer Powers Guardians Past Orioles

On July 21, 2025, the Cleveland Guardians defeated the Baltimore Orioles 10-5 at Progressive Field, improving their record to 49-50 and holding second place in the AL Central. The Orioles, now 44-55,

Associated Press News on MSN · 17h

José Ramírez’s 3-run homer sparks Guardians’ 10-5 win over Orioles

José Ramírez had a three-run homer in the first inning, Brayan Rocchio delivered a two-run single in the seventh and the Cleveland Guardians pulled away for a 10-5 victory over the Baltimore Orioles.

22h

Guardians score, recap vs Orioles | Cleveland pounds Baltimore with 10-run game

The Guardians and Orioles open a four-game homestand July 21 at Progressive Field. Follow along here for live updates and ...

11hon MSN

Cleveland Guardians and Baltimore Orioles meet in game 2 of series

Baltimore has a 44-55 record overall and a 22-30 record in road games. The Orioles have a 26-45 record in games when they ...

15hon MSN

Guardians waste scoring chances, but produce in the clutch against Orioles; Kwan, Gaddis return

The Guardians (49-50) have won nine of their last 11 games since ending their 10-game losing streak. They trail first-place ...

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