If the Buffalo Bills can't deal with Derrick Henry, Lamar Jackson, and the Baltimore Ravens' marvelous, multiple run game, an early postseason exit could be the result.

With leading receiver Zay Flowers out with a knee injury, Baltimore can't forget about the All-Pro it has in the backfield vs. Pittsburgh.

The Ravens running back rushed for a season-high 199 yards in Week 4. But the Bills now have three key pieces back on defense.