In order for the pair of wings and the pair of halteres (as well as all other parts of the fly) to develop properly, the fly's suite of Hox genes must be expressed in a precise way and at precise ...

Hox genes and their relatives are involved in several developmental processes in diverse animals, but when did they first arise? The genome sequence of the sponge Amphimedon queenslandica shows ...

In particular, biologists have suspected that the insects' progression to six legs, and the evolution and modification of arthropod appendages in general, are driven by changes in Hox gene activity.

The hallmark expression of Hox genes along anterior–posterior body regions has motivated many fruitful molecular studies into how animal bodies are patterned, but 40 years of research into Hox ...

Osamu Chisaka (University of Utah School of Medicine, Salt Lake City): “This paper is the first report about mice with an inactivated Hox gene— mammalian homologues of fruit fly homeotic genes that ...