Researchers at Tel Aviv University (TAU) can add to that list their important discovery of a cancer mechanism that has been ...

triggering the immune system to focus its attention on killing cancer cells in mouse models of breast cancer and melanoma. "RIG-I is commonly activated to help the body combat viral infections and ...

A team has re-engineered immune cells with a light-activated switch that modulates protein function and cellular behavior. When exposed to blue light, the cells change shape, infiltrating solid tumors ...

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T ...

Image DOI: 10.7295W9CIL38960 Researchers at the University of Tokyo studied a cell membrane receptor, LRP1, and an enzyme, tPA, for their roles in metastasis of melanoma in mice. Disclaimer ...

Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can ...

Curr Cancer Drug Targets. 2017;17:1-15; Zhang et al. Tanapoxvirus lacking a neuregulin-like gene regresses human melanoma tumors in nude mice. Virus Genes. 2017;53: 52-62; Zhang T and Essani K.

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells -; which have lost their cancer-fighting oomph -; consume this lactic ...

We investigate the efficacy of a combination of chemotherapy and immunotherapy using melanoma mouse models and human melanoma specimens. 3) The roles of amino acid transporters in cancer development ...

Less frequent IV dosing with nemvaleukin in patients with select advanced solid tumors, including ovarian cancer and mucosal melanoma, showed ...