At intervals of five to nine days, healthy volunteers were given two 12.5-mg promethazine rectal suppositories, one 25-mg suppository ... request from the Food and Drug Administration.

The pharmacokinetics of promethazine administered ... [a] Phenergan 12.5-mg rectal suppository, Wyeth-Ayerst Laboratories, Radnor, PA, lot 9940524. [b] Phenergan 25-mg rectal suppository, Wyeth ...