GTP is also a substrate for the synthesis of RNA during transcription. Purine metabolism involves the synthesis and breakdown of purine nucleotides in cells. Disorders of purine metabolism can lead to ...

Hyperuricemia (HU), characterized by elevated uric acid (UA) levels in the blood, is a global health concern associated with various conditions, including cardiovascular diseases, gout, hypertension, ...

How to Reduce Uric Acid Levels Through Diet Uric acid is a waste product produced in the body from the breakdown (metabolism) of purines. Purines are normally produced in the body and found in ...

Forty % of sudden infant death syndrome (SIDS) babies have higher hypoxanthine (Hx) cone, in their vitreous humor than respiratory distress syndrome (RDS) babies (unpublished data). To investigate ...

They soon discovered, from observing the role of purines in nucleic acid metabolism, that bacterial cells require certain purines to make DNA. Hitchings hypothesized that by preventing those purines ...

Recent studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. This prospective study ...

Hyperuricemia (HU) is a metabolic disorder characterized by elevated uric acid (UA) levels in the bloodstream, commonly diagnosed when UA levels exceed 420 µmol/L (7 mg/dL) in men and 350 µmol/L (6 mg ...