Guanine is also a component of important biomolecules such as GTP (guanosine triphosphate), which is involved in cellular signaling and protein synthesis. In addition to their role in nucleic acids, ...

By analyzing the blood and cerebrospinal fluid (CSF) of the patients, researchers have discovered critical impairments in purine metabolism and the recycling of adenosine triphosphate (ATP)-;the ...

Adenylosuccinate lyase deficiency (ADSLD) is a rare genetic disorder that affects purine metabolism, leading to various neurodevelopmental issues. Purines are essential building blocks for DNA and ...

Purine nucleotides are essential for cell growth and function as they serve as nucleic acid building blocks, signaling molecules, and energy carriers. Treatments that inhibit their synthesis offer a ...