The Spanish giant saw its UEFA Champions League title defense come to an end Wednesday night at the Santiago Bernabéu Stadium. Arsenal won 2-1 to advance by a 5-1 aggregate score. It's the first time since the 2019-20 season Madrid failed to reach the UCL semifinals.

Real Madrid will not win their 16th Champions League title this season after being dumped out of the competition by Arsenal. The second leg at the Santiago Bernabeu finished 2-1 to the visitors,

Arsenal ended Real Madrid's European title defense after eliminating the Spanish giants 5–1 on aggregate in the Champions League quarterfinals.