The San Francisco 49ers are once again hampered ... Brock Purdy and Kyle Shanahan to pull off some magic against the Buffalo Bills if they want a shot at redemption. The Buffalo Bills have the ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6). San Francisco has ...

Buffalo Bills and San Francisco 49ers reveal game-day inactives as both teams prepare for winter wonderland matchup at Highmark Stadium. The Buffalo Bills (9-2) prepare for a critical Week 13 ...

Here's everything you need to know when the San Francisco 49ers play the Buffalo Bills Week 13 of the 2024 NFL season. Here's everything you need to know when the Kansas City Chiefs play the ...

There won't be a Bosa family reunion in the Bay Area. The Buffalo Bills are reportedly signing former Chargers pass rusher Joey Bosa to a one-year, $12.6 million deal. ESPN source: Five-time Pro ...

As we all know, not every selection works as planned. That's the case with these 32 players identified by SI.com's Matt ...

All 32 teams will have a guest announce their Day 2 NFL draft picks, and for the San Francisco 49ers it will be a former ...

Dec 1, 2024; Orchard Park, New York, USA; Buffalo Bills linebacker Matt Milano (58) leaps for a pass against the San Francisco 49ers during the second half at Highmark Stadium. / Gregory Fisher ...

San Francisco ... 49ers are signing Neal to a two-year contract, Cameron Wolfe of NFL Network reports. To this point, Neal had spent his entire NFL career in the AFC, playing six seasons with ...

Yates' second pick for the 49ers also makes sense in a vacuum. He has San Francisco selecting Minnesota's Aireontae Taylor with the 43rd overall pick. This would also be a bit of a reach according to ...

Following their gut-wrenching defeat to the Kansas City Chiefs in Super Bowl 58, the San Francisco 49ers expected to embark on another deep playoff run in the 2024 season and end their 30-year ...