Welcome to Brainland, the bustling, 24/7 theme park in your head. There’s Memory Maze, Logic Log Flume, and of course, the ...

New research suggests that Huntington’s disease could cause the brain to rewire, like a road detour. While connections between some brain cells are shut down, the traffic seems to get re-routed, ...

We’ve been following the development of uniQure’s HTT-lowering drug, AMT-130, from its genesis in the lab, to animal studies just a few years ago, and now through to their ongoing Phase 1/2 clinical ...

We’re pleased to announce the 2025 HDBuzz Prize! This year, the HDBuzz Prize is brought to you by the Hereditary Disease Foundation (HDF), who are sponsoring this year’s competition. Training the next ...

COVID-19 update: what does it mean for HD families, how does it impact HD research, and how has it changed the way science works? Wave Life Sciences announces that its antisense drug WVE-120102 has ...

HDBuzz helps untangle some bold claims about the just-announced results of the PRIDE-HD trial of pridopidine in HD ...

Prana Biotech's PBT2 trial in Huntington's disease: what we know so far & what copper has to do with the mutant prote ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

This week, we heard an update from Roche about their huntingtin-lowering therapy, tominersen, currently being tested in the GENERATION HD2 trial. An independent data monitoring committee (iDMC) that ...