In vivo visualization of inflammatory lesions has been revolutionized by PET with 18 F-FDG as a tracer and by MRI with gadolinium-labeled contrast media. Apart from other indications, 18 F-FDG PET and ...

Radiopharmaceuticals Good manufacturing practice–grade PSMA-11 and PSMA-617 were obtained from ABX. 225 Ac was produced by radiochemical extraction from 229 Th (9,10). 68 Ga was eluted from a 68 Ge/ ...

Antiamyloid therapies for Alzheimer disease recently entered clinical practice, making imaging biomarkers for Alzheimer disease even more relevant to guiding patient management. Amyloid and tau PET ...

The principle of pretargeted radioimmunoimaging and therapy has been investigated over the past 30 y in preclinical and clinical settings with the aim of reducing the radiation burden of healthy ...

Journal of Nuclear Medicine April 2025, jnumed.124.268980; DOI: https://doi.org/10.2967/jnumed.124.268980 ...

Large language models (LLMs) are poised to have a disruptive impact on health care. Numerous studies have demonstrated promising applications of LLMs in medical imaging, and this number will grow as ...

Journal of Nuclear Medicine June 2025, jnumed.125.269655; DOI: https://doi.org/10.2967/jnumed.125.269655 ...

The use of brain PET in research has spanned more than 5 decades. PET has been shown to be a valuable tool for assessing changes in flow, metabolism, and receptor occupancy resulting from ...

The widespread use of 223 Ra-dichloride (Xofigo; Bayer) and 177 Lu-DOTATATE (Lutathera; Advanced Accelerator Applications) has rejuvenated radiopharmaceutical therapy (RPT) of cancer. RPT delivers ...

Journal of Nuclear Medicine February 2025, jnumed.124.268967; DOI: https://doi.org/10.2967/jnumed.124.268967 Cancer therapy has advanced with molecularly targeted ...

Dual-Tracer Imaging on a Long–Axial-Field-of-View PET: A Proof-of-Principle Study with [18 F]FGln and [18 F]FDG ...

The radionuclide gastric-emptying study has long been the standard clinical diagnostic test for the detection of gastroparesis. Both solid and liquid studies have been used over the years, either as ...