Popular cruise lines for U.S. river cruises include American Cruise Lines, Viking River Cruises, and National Geographic Expeditions.

This 12-day Viking itinerary from New Orleans to Memphis is one of the most popular, if not the most popular, Mississippi River cruise that Viking offers, according to staff. Guests on this ...

The more than 2,300-mile Mississippi River invites travelers to discover its multifaceted heritage, with a vast range of deeply rooted culture, music and history. A cruise is a fantastic way to ...