Ester-based agents like benzocaine were linked to a considerably higher risk of serious adverse events (OR: 7.85, 95% CI: 4.81 to 12.91). However, amide-based agents like lidocaine (OR: 0.59, 95% CI: ...

Despite the frequent use of lidocaine as an anesthetic and its ... balsam of Peru 25% (2 cases), dibucaine 2.5% (1 case), and benzocaine 5% (1 case). Patch tests with lidocaine dilutions (in ...

Pertinent negative reactions to the amides dibucaine 2.5% and prilocaine 2.5% and to the esters benzocaine 5% and tetracaine 1% were observed. Intradermal test results with lidocaine 1% ...