U.S. FDA grants Orphan Drug Designation to Deramiocel for the treatment of Becker Muscular Dystrophy, broadening Capricor’s ...

U.S. FDA successfully completed Pre-License Inspection; Company expects facility will meet all requirements to support licensure Advisory Committee meeting scheduled for July 30, 2025 Mid-cycle ...

Researchers have developed a novel method for simultaneously recording action potentials (APs)—temporary changes in ...

It certainly wasn’t on the Thomases’ radar when their 2-year-old son went into sudden cardiac arrest in the middle of the night at their Illinois home. When the child woke up screaming ...

But BridgeBio won approval for Attruby, a drug with the same mechanism of action as tafamidis ... ATTR-CM causes stiffening of cardiac muscle and heart failure, leading to death in around 2.5 years if ...

Extracellular matrix; Central nervous system; Cerebellum; Neuron; Migration The action potential (AP) is the triggering signal for contraction in striated muscle. Ion currents ... In a typical ...

Researchers have identified a significant growth factor with regenerative potential for cardiac muscle cells. (Photo: ANI) Heart muscle cells are significantly lost following heart traumas ...

Figure 2 Proposed mechanisms of action of (stem) cell therapy. The cartoon summarizes the main mechanisms claimed to underline the potential benefits of (stem) cell therapy. While cardiac regeneration ...

Other causes include myocarditis or inflammation of the heart muscle ... Cardiac arrest is different from a heart attack, which occurs when blood flow to the heart is blocked. Fast action saves ...

Next, the same muscle was bathed (at least for 30 min ... First, the effects of PA and NAPA on Vmax and HDT of the cardiac action potential were systematically and comprehensively compared using ...

In preclinical and phase 1 studies, it demonstrated the potential ... or regenerate cardiac tissues? Danielson: VEGF is a well-known angiogenic factor; its biological method of action is primarily ...

These materials possess potent regenerative properties and have the potential to repair and restore function to a wide range of injured and diseased tissues including cardiac and skeletal muscle ...