Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a ...

Aside from direct metabolism of purines, Dodd’s group has identified an additional pathway that some microbes can use to break down urate into short-chain fatty acids. His group cultured various ...

The evolutionary loss of uricase activity in humans and certain primates completely blocks the degradation of soluble uric acid (sUA), leading to higher physiological levels of sUA than in other ...

Parkinson's disease is a neurodegenerative condition that affects an individual's brain, causing issues with their movement, sleep and mental ...

Disruptions in Purine Metabolism Cited in Parkinson’s Development Written by Investor Brand Network Written on Oct 2, 2024 ...

By assessing the levels of purine metabolites, including inosine, hypoxanthine, xanthine, and uric acid, using a technique called targeted metabolomics, they found that patients with PD have ...

Boban M, et al., Circulating purine compound, uric acid, and xanthine oxidase/dehydrogenate relationship in essential hypertension and end stage renal disease., Ren. Fail., 36, 613, 2014 ...

The key pathways involved in Shenkang injection on serum metabolites of UUO mice are the biliary secretion pathway, metabolism of taurine and low taurine, steroid metabolism, phenylalanine metabolism, ...

Purines are basic building blocks of the cell. Disturbances of the purine metabolism in the cell have already been associated with some disease patterns in the past.

Purines are basic building blocks of the cell. Disturbances of the purine metabolism in the cell have already been associated with some disease patterns in the past.