For the downregulated metabolites, the top 5 enriched terms were Galactose Metabolism, Glycolysis, Purine Metabolism, Fructose and Mannose Degradation, and Gluconeogenesis. In this study, we explored ...

So far as is known today, uric acid serves no biochemical function in the body other than being an end product of purine metabolism. The metabolically important purines, adenine and guanine ...

Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW 2145, Australia Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, ...

Cardiac, renal, and metabolic (CRM) conditions are major causes of morbidity and mortality globally. This study aims to explore the relationship between serum uric acid (SUA), hyperuricemia, gout, and ...

Pathways and enzymes of polyamine synthesis. Surface motility of W3110. (A) Surface motility of parental and derivative strains lacking the major subunits of the flagella (FliC), pili (FimA), or both.

Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing, China (Longbin Zheng, X.C., X.H., Y.T., J.M ...

Correspondence to: Prof. Yafei Liu, Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, Henan 450001 ...

Purine nucleotides are essential for cell growth and function as they serve as nucleic acid building blocks, signaling molecules, and energy carriers. Treatments that inhibit their synthesis offer a ...

Consequently, they are fundamental components of our bodies and vital for physiological functions such as protein synthesis, tissue repair and nutrient absorption. Here we take a closer look at amino ...