Non-transfusion-dependent thalassemia encompasses three clinically distinct forms -- beta-thalassaemia intermedia, hemoglobin E/beta-thalassaemia ... endpoint -- a ≥1.0 g/dL increase in mean ...

Non-transfusion-dependent thalassemia encompasses three clinically distinct forms -- beta-thalassaemia intermedia, hemoglobin E/beta-thalassaemia (mild and moderate forms), and al ...

On investigation, he was found to have low hemoglobin (Hb: range ... High-performance liquid chromatography was negative for beta-thalassemia with Hb A 2 of 2.8%, Hb F of 1.4% and no other abnormal Hb ...

This procedure during pregnancy was associated with fewer admissions for pain crises (p=0.032), higher gestational age at delivery ... in patients with severe SCD (45 Hb SS plus 2 Hb Sβ0-thalassemia ...

The FDA approved betibeglogene autotemcel (beti-cel; Zynteglo) for adult and pediatric patients with transfusion-dependent ...

Thalassemia is a genetic blood disorder that affects hemoglobin production, leading to severe anemia and requiring lifelong medical management, including regular blood transfusions. The impact of ...

There were no serious adverse events or treatment-related mortalities. Evidence Rating Level: 2 (Good) Study Rundown: Transfusion-dependent β-thalassemia (TDT) is a condition that results in iron ...

A Thalassemia screening desk has been inaugurated at the NADRA centre in Sukkur on Saturday marking a significant step forwards the fight against the genetic disorder. The desk, established in ...

Genetic mutations in the β-globin gene lead to a decrease or removal of the β-globin chain, causing the build-up of unstable alpha-hemoglobin. This condition is referred to as beta-thalassemia (BT).

Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.