Super-immunodeficient mice as well as advanced humanized models have enabled a deeper understanding of disease mechanisms and accelerated the development of novel therapeutics that have a greater ...

Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human ...

The supplement, called microbiota-directed complementary food, or MDCF-2, contains chickpea flour, peanut flour, soy flour, ...

The study, conducted using a humanized mouse model, focused on understanding BDP’s impact on leukemia cells’ response to ...

The ATX-Gx platform, which enables best-in-class in-vivo human antibody discovery, comprises multiple strains of mice that have been engineered to express human antibody genes. These humanized mice ...

Antengene Corporation Limited ("Antengene", SEHK: 6996.HK), a leading innovative, commercial-stage global biopharmaceutical ...

AnaptysBio has a past history of successes. There are 2 molecules in phase 2, but with no patient data. GSK news has hurt ANAB stock. Read more here.

Carisma Therapeutics Inc. (Nasdaq: CARM) ("Carisma" or the "Company"), a clinical-stage biopharmaceutical company focused on discovering and developing innovative immunotherapies, today announced ...

These are being tested in humanized mice and NHPs. Holmes reported 76% allele correction in HSCs, which he judged to be “an incredible accomplishment.” “We’re now up to 52% editing of ...

In both syngeneic and humanized tumor models, systemic administration of anti-GPC3 CAR mRNA/LNP significantly reduced tumor burden and suppressed metastasis to the liver. The therapy was well ...

At the 2024 Annual Meeting of the Society for Immunotherapy of Cancer (SITC 2024), held in Houston, USA, from , Akeso Biopharma (9926. HK) presented the mechanism of action (MOA) research findings of ...