Febuxostat is a novel non-purine selective inhibitor of xanthine oxidase for ... on other enzymes associated with purine and pyrimide metabolism. The most frequent adverse events reported in ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The DNA blueprint is carefully read, transcribed, and ...

New research from the Royal Veterinary College (RVC) has identified porcupine inhibition—a strategy that blocks a key ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Corticosteroid therapy induces clinical, laboratory and histological improvements in 80% of patients with autoimmune hepatitis. Prednisone, alone or at a lower dose in combination with ...

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing ...

Some gut–brain neuromodulators are efficacious in reducing global symptoms and abdominal pain in IBS. The findings support ...