With every team's 2025 schedule finalized, oddsmakers have released betting odds for all 16 Week 1 games this fall, starting with Cowboys vs. Eagles on Sept. 4.

Moreover, it gave oddsmakers the chance to set point spreads and totals on every single Week 1 NFL contest and, accordingly, football bettors the opportunity to analyze and scalp early value on live NFL sportsbook odds.

The Saints lost one quarterback to retirement, meaning a new one will be under center come Week 1. Who will it be? See the latest odds.