DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Adenine and guanine are double-ring molecules called purines ... in their structure. The deoxy- means that on one side of the base pair, there's a place where another base pair can attach itself ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

In addition, they show that pyrimidine nucleotides can functionally inhibit UCP1 proton conductance to a similar extent as purine nucleotides. Comparison with the GTP structure shows that the UTP ...

Whether you want to follow along perfectly, or use the base structure of the tree to go your own way, this is the kind of house build that everyone will notice, and for good reason. If you would ...

After hours: March 21 at 6:15:26 PM EDT Loading Chart for BASE ...

Heart failure with preserved ejection fraction (HFpEF) constitutes more than half of all HF but has few effective therapies. Recent human myocardial transcriptomics and metabolomics have identified ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During DNA replication, the DNA polymerases ...