Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW 2145, Australia Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

which requires sufficient quantities of purines and pyrimidines. Upon analyzing the levels of 3,000 genes in a T cell leukemia cell line grown in high or low levels of glucose, Possemato and his team ...

Cells sustain their purine levels through two pathways: De novo synthesis builds purines from scratch ... salvage pathway could be an access route for cancer cells to get their nucleotide supply when ...