Purine nucleotides are considered to be the only inhibitors of UCP1 activity, binding to its central cavity to lock UCP1 in a proton-impermeable conformation. Here we show that pyrimidine nucleotides ...

Two nucleotides together form a base pair ... Adenine and guanine are double-ring molecules called purines, but cytosine, thymine and uracil are all pyrimidines: single rings.

Extracellular and intracellular adenine nucleotides (ANs) act as paracrine mediators or ... summarized the role of extracellular vesicles containing ectonucleotidases and other purine-metabolizing ...

Alternatively, using 9-Aminoacridine (9AA) as a matrix, purine and pyrimidine nucleotide mono–, di– and triphosphates can be imaged to obtain pixel-by-pixel ratios of nucleotides with different ...

One of the main factors contributing to high uric acid levels in the body is an unhealthy diet. Certain foods contain high levels of purines—compounds that break down into uric acid. Overconsumption ...

High uric acid levels can lead to gout and kidney stones, but certain dry fruits can help manage these levels. Including these dry fruits in your diet can be a tasty and effective way to manage ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein synthesis is an essential process, ...

The RNA Institute, University at Albany, State University of New York, Albany, New York 12222, United States Department of Biological Sciences, University at Albany, State University of New York, ...

Sixth People’s Hospital, School of Medicine & School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, P. R. China Centre for Personalized Nanomedicine, Australian Institute ...

1 Division of Molecular and Genetic Medicine, Royal Hallamshire Hospital, Sheffield, UK 2 Gastroenterology and Liver Unit, Royal Hallamshire Hospital, Sheffield, UK 3 Gastroenterology Unit, John ...