The San Francisco 49ers are once again hampered ... Brock Purdy and Kyle Shanahan to pull off some magic against the Buffalo Bills if they want a shot at redemption. The Buffalo Bills have the ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6). San Francisco has ...

Buffalo Bills and San Francisco 49ers reveal game-day inactives as both teams prepare for winter wonderland matchup at Highmark Stadium. The Buffalo Bills (9-2) prepare for a critical Week 13 ...

Here's everything you need to know when the San Francisco 49ers play the Buffalo Bills Week 13 of the 2024 NFL season. Here's everything you need to know when the Kansas City Chiefs play the ...

Watch all of the Buffalo Bills' top plays from their AFC East-clinching win over the visiting San Francisco 49ers on "Sunday Night Football" during Week 13 of the 2024 NFL regular season.

The Buffalo Bills are set to have a classic snow game matchup against the San Francisco 49ers in Orchard Park. The Buffalo Bills will look to build on their six-game win streak when they host the ...

The Baltimore Ravens and San Francisco 49ers are tied for the most picks in the 2025 NFL draft with 11 selections each. San ...

San Francisco ... 49ers are signing Neal to a two-year contract, Cameron Wolfe of NFL Network reports. To this point, Neal had spent his entire NFL career in the AFC, playing six seasons with ...

All 32 teams will have a guest announce their Day 2 NFL draft picks, and for the San Francisco 49ers it will be a former ...

Following their gut-wrenching defeat to the Kansas City Chiefs in Super Bowl 58, the San Francisco 49ers expected to embark on another deep playoff run in the 2024 season and end their 30-year ...