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Objectives Emerging evidence suggests that the microbiome plays an important role in the pathogenesis of osteoarthritis (OA). We aimed to test the two-hit model of OA pathogenesis and potentiation in ...
Objectives MAXIMISE (Managing AXIal Manifestations in psorIatic arthritis with SEcukinumab) trial was designed to evaluate the efficacy of secukinumab in the management of axial manifestations of ...
Background An important but often insufficient aspect of care in people with inflammatory arthritis (IA) is empowering patients to acquire a good understanding of their disease and building their ...
Objectives To report the level and trends of prevalence, incidence and years lived with disability (YLDs) for osteoarthritis (OA) in 195 countries and territories from 1990 to 2017 by age, sex and ...
1 Wonkwang University Medical School, Internal Medicine, Iksan, Korea, Rep. of (South Korea) 2 Jeonbuk National University Medical School, Internal Medicine, Jeonju, Korea, Rep. of (South Korea) ...
Objectives Clinical heterogeneity is a cardinal feature of systemic sclerosis (SSc). Hallmark SSc autoantibodies are central to diagnosis and associate with distinct patterns of skin-based and ...
1 INSERM, U1059-SAINBIOSE, University of Lyon, Saint-Etienne, France 2 University Hospital of Saint-Etienne, Rheumatology, Saint-Etienne, France Background Methotrexate (MTX) is the recommended ...
Background The trend of, and the impact of major organ damage on the short- and longer-term survival of patients with systemic lupus erythematosus (SLE) globally over the past 60 years have not been ...
Objective Gout is characterised by severe interleukin (IL)-1-mediated joint inflammation induced by monosodium urate crystals. Since IL-37 is a pivotal anti-inflammatory cytokine suppressing the ...
Objectives: To investigate dynamics of B-cell subsets in SLE patients treated with or without BLM, with a focus on assessing MBC characteristics. Results: By employing HS flowcytometry, we established ...
1 The Artic University of Norway, Department of Health Science, Tromsø, Norway 2 University Hospital of North Norway, Department of Rheumatology, Tromsø, Norway 3 UiT, The Artic University of Norway, ...
Objectives Oligoarticular psoriatic arthritis (PsA) is frequent but rarely studied. The objective was to assess the efficacy of apremilast in early oligoarticular PsA. Methods FOREMOST (NCT03747939) ...
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