Many learners are more facile with the use of large language models in medicine than their supervisors are. The authors ...

The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

Despite their limited experience, medical students and residents are often sought out for health advice by family and friends. In an inequitable health system, these consults may seem essential.

A 39-year-old man presented with a 1-day history of lower abdominal pain. The blood pressure was 203/132 mm Hg. Imaging revealed a retroperitoneal mass inferior to the aortic bifurcation.

A new Massachusetts law may be the most far-reaching U.S. state legislation aimed at curtailing the influence of private equity in health care. It could serve as a model for other jurisdictions.

Audio Interview from the New England Journal of Medicine — Interview with Tom Frieden on the role of the CDC and current threats to the U.S. public health infrastructure.

MASLD has become the most common chronic liver disease worldwide. The authors review the features of the disease as well as pharmacotherapies targeting the associated liver and cardiovascular ...

Risdiplam, an oral pre–messenger RNA splicing modifier, is an efficacious treatment for persons with symptomatic spinal muscular atrophy (SMA). The safety and efficacy of risdiplam in ...

A small-molecule drug proves its mettle in the treatment of spinal muscular atrophy, a disease amenable to intervention at the pre-mRNA level.

A 47-year-old woman presented with a 1-month history of headaches and blurry vision. An MRI of the head showed an enlarged pituitary gland protruding from the sella turcica, known as the ...

This feature about a man with obesity offers a case vignette accompanied by two essays, one supporting initiation of semaglutide therapy and the other recommending bariatric and metabolic surgery.