Lipids Open the Door. Microglial cells treated with unlipidated (top) or lipidated (bottom) ApoE (yellow) along with fluorescently tagged Aβ (green). Lipidated ApoE was more readily internalized and ...
New research shows that microglia, which usually clear debris, cause harmful inflammation in the presence of APOE4 protein.
In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for ...
Scientists at Gladstone Institutes created a new research model for studying Alzheimer’s that involved transplanting human neurons producing the APOE4 protein into the brains of mice. They found that ...
A team of scientists has found that the presence of the APOE4 protein -- the most important genetic risk factor for Alzheimer ...
Taurine may decrease atherosclerotic plaque size and enhance vascular stability, as shown in studies on humans and mice. Previous research has suggested that taurine supplementation could help slow ...
The link between lipid metabolism and glaucoma pathophysiology could guide future research and treatment strategies.