The conventional view of memory consolidation predicts that blockade of protein synthesis should block new learning in test 1 of these experiments, which is an extinction test. The only new ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Here, the authors reveal that telomere synthesis is bidirectionally constrained by cellular nucleotide pools, in a manner which may be therapeutically manipulated. Mitochondrial DNA polymerases ...

Department of Pharmaceutical Sciences, Department of Chemistry and Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697-3958, United States Article ...