GAS2 is a cytoskeletal regulator that interacts with both F-actin and microtubules. Here, cryo-EM structures of GAS2 domains ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Additionally, the writing meets basic writing guidelines such as maintaining sentence structure that keeps the subject and verb close together at the start of the sentence. Captivating Audience in ...

Abstract: Accurate identification of protein-nucleotide binding residues is essential for protein functional annotation and drug discovery. Advancements in computational methods for predicting binding ...

We first carried out PCA to uncover an overview of the genetic structure of East Asians and Southeast Asians (Figure 2). The top two PCs (PC1 and PC2) revealed that within present-day populations, ...

2022). I investigated whether base reactivities and secondary structure models derived from them can explain some variability in the frequency of observing different nucleotide substitutions across ...

We are analyzing primary and relapsed ALL from the same patient, with the aim of determining the clonal structure of the leukemia and characterize the cancer stem cell population in the primary sample ...

Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, United States Department of Biochemistry and Structural Biology, University of ...

While the contacts are crystallographically well defined, the possibility that the observed conformation of these residues reflects crystal packing constraints, and an alternate structure exists ...

These therapies, which form standard-of-care for many cancers, typically kill tumour cells by targeting pan-essential pathways, principally metabolism of the DNA molecule or its nucleotide building ...

There are 20 amino acids that make up proteins and all have the same basic structure, differing only in the R-group or side chain they have. Amino acids are in an equilibrium between two acids with ...