Purine Metabolism: The series of biochemical processes involved in the synthesis, recycling, and degradation of purine nucleotides.

Worried about protein and uric acid? Experts clarify the link. Purines, not all proteins, elevate uric acid. Red meat and ...

A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São Paulo, Brazil) presents a valuable new experimental model for investigating ...

Antimetabolites Antimetabolites are inhibitors of purine synthesis; they include the prodrug azathioprine, which is converted to its active metabolite 6-mercaptopurine.

The expeditious convergent synthesis of the potent human purine nucleoside phosphorylase inhibitor DADMe-Immucillin-G (3) was achieved via the Mannich reaction. The Mannich chemistry of a series of ...

Furthermore, DDAP has been successfully used for real-time tracking the uptaking and degradation of albumin in ex vivo mouse kidney models for the first time. All these results clearly demonstrated ...

This work evaluated the catalytic activity of TiO2 synthesized by the Pechini method. with varying molar ratios of 2:1, 3:1 and 4:1 of citric acid/metallic cations, in the photocatalytic degradation ...

However, one-carbon metabolism contributes to many cellular processes, including purine synthesis, amino acid metabolism, and phospholipid synthesis, among others 53, so it is likely that one-carbon ...

Changes in Secondary Metabolism Upon P. sojae Infection Changes in secondary metabolism are mainly concentrated in pathways centered on benzoate degradation (Figure 6A), purine metabolism (Figure 6B) ...

Methotrexate has multiple mechanisms of action that complement teriflunomide's inhibition of de novo pyrimidine synthesis, including inhibition of purine synthesis, increased release of adenosine ...