Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a ...

Researchers have identified separate gut bacteria species that can metabolize purines and urate, suggesting that microbial pathways might be leveraged through probiotics to reduce hyperuricemia.

CD38 inhibition is restricted to sUA in purine metabolism, and a structural comparison using methyl analogs of sUA such as caffeine metabolites shows that 1,3-dihydroimidazol-2-one is the main ...

Parkinson's disease is a neurodegenerative condition that affects an individual's brain, causing issues with their movement, sleep and mental ...

Parkinson’s disease is a neurodegenerative condition that affects an individual’s brain, causing issues with their movement, sleep and mental health. Common symptoms include tremors, slowed ...

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.

XORTX is working to advance its clinical development stage products that target aberrant purine metabolism and xanthine oxidase to decrease or inhibit production of uric acid.

4) Shenkang injection can regulate the metabolism of amino acid, purine, and fatty acids in UUO mice. 2 Introduction Renal fibrosis is a complex and irreversible pathological process that involves the ...

Purines are basic building blocks of the cell. Disturbances of the purine metabolism in the cell have already been associated with some disease patterns in the past.

Purines are basic building blocks of the cell. Disturbances of the purine metabolism in the cell have already been associated with some disease patterns in the past.