Today's super-resolution microscopes have made it possible to observe the nanoscale world with unprecedented detail. However, ...

This includes studying interactions within organoids, organs and even whole organisms. With light sheet microscopy, you can image a sample as large as a whole mouse, in 3D, at cellular resolution ...

This causes the molecules in the sample to move apart evenly and also become larger, so that they can be imaged with a light microscope after being specifically labeled with fluorescent molecules.

as there is no need for fixation or RNase treatment. Nuclear-ID Red DNA stain is compatible with a broad range of instruments, including conventional and confocal fluorescence microscopes ...

The Milestones aim to highlight the most influential developments in light microscopy in a series of short articles, each describing a major achievement. Nature Milestones in Light Microscopy also ...