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Retro Baltimore: Baltimore rat expert once used mice to predict humans would be extinct by 2027
While the name of John Bumpass Calhoun might not be familiar to everyone these days, he and his life’s work — studying rats ...
Inhibiting METTL3 protein shows promise for high-risk neuroblastoma
Blocking the METTL3 protein can increase sensitivity to chemotherapy in neuroblastoma, according to research from the ...
News Medical4d
New approach reinvigorates exhausted T cells to improve tumor control
As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells -; which have lost their cancer-fighting oomph -; consume this lactic ...
GEN4d
Cancer-Fighting Zeal Regained by Tired T Cells Deprived of Lactic Acid
Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can ...
New take on immunotherapy reinvigorates T cells by blocking uptake of energy-sapping cancer byproducts
As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T ...
Mural Oncology Presents Clinical and Preclinical Data Across its Pipeline at the 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC)
Less frequent IV dosing with nemvaleukin in patients with select advanced solid tumors, including ovarian cancer and mucosal melanoma, showed ...
Lisata Therapeutics and Valo Therapeutics Announce Preclinical Research Collaboration
Study will investigate the benefits of combining Lisata's novel product candidate, certepetide, with ValoTx's platform technology, PeptiCRAd, and a checkpoint inhibitor in preclinical tumor ...
Lisata Therapeutics, Valo Therapeutics enter preclinical research collaboration
Lisata Therapeutics (LSTA) and Valo Therapeutics announced a preclinical research collaboration to investigate the benefits of combining ...