DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Among these, ABC transporters, nucleotide metabolism, glycine-serine-threonine metabolism, biosynthesis of amino acid, purine metabolism, pyrimidine metabolism, and carbon metabolism were ...

There is considerable evidence for a role for metabolic dysregulation, including disordered purine nucleotide metabolism, in the pathogenesis of Alzheimer’s disease (AD). Purine nucleotide synthesis ...

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Short-circuitry of brown adipose mitochondria by proton leak through activated human uncoupling protein (UCP1) leads to heat production and this process is thought to be inhibited specifically by ...

Schematic workflow of metabolite ratio imaging using pixel data from Bruker SCiLS Lab API or imzml file from any MSI data source. For SCiLS lab MSI data, the execution of R codes starts with ...

UA metabolic pathways. Ingested and endogenously produced purines impose a significant strain on the body’s purine nucleotide synthesis processes, culminating in the accumulation of intermediates such ...

These therapies, which form standard-of-care for many cancers, typically kill tumour cells by targeting pan-essential pathways, principally metabolism of the DNA molecule or its nucleotide building ...

Cytosolic Ric-8A has guanine nucleotide exchange factor (GEF) activity and is a chaperone for several classes of heterotrimeric G protein α subunits in vertebrates. Using Hydrogen-Deuterium ...

This causes different cell types, such as intestinal cells, to have increased susceptibility to MPA by relying more heavily on the de novo synthesis of purine nucleotides. [37] ...