Solution-phase organic reactions form the backbone of organic synthesis. Compared to solid-phase and gas-phase methods, ...

Terremoto Biosciences Inc. has synthesized new 3H-imidazo[4,5-b]pyridine compounds acting as RAC-α serine/threonine-protein kinase (AKT1; PKB-α) inhibitors reported to be useful for the treatment of ...

Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Bangkok 10400, Thailand ...

WHILE investigating products in cultures of a strain of Bacillus subtilis, we obtained a crystalline substance which sublimed very easily even at ordinary temperature and had the characteristic ...

Small, polar rings and electron-withdrawing atoms are both well-loved motifs in medicinal chemistry. So oxetanes and fluorine atoms could be a match made in drug discovery heaven. Researchers also ...

Following this strategy, they determined that the best candidate was a well-designed Fe-SAC with a high loading of Fe-pyridine-N4 sites (~3.83 wt%) and highly mesoporous structure. It successfully ...

Get Instant Summarized Text (Gist) A data-driven approach has been used to accelerate the development of single-atom catalysts (SACs) for water purification, overcoming the limitations of ...

Imperial Chemical Industries, Ltd. ( Fielden, R. J., Homer, R. F., and Jones, R. L. ), British Patent Specification No. 785,732.

In a study appearing in Nature Chemistry, UC Davis researchers report the successful total synthesis of ibogaine, ibogaine analogs, and related compounds from pyridine — a relatively inexpensive and ...

CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (NCNST), Beijing 100190, China Center ...