Imdelltra is associated with improvement in overall survival compared to local standard-of-care chemotherapy among patients with small cell lung cancer.

A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team ...

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders ...

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal ...

"It's much like doing a medical CT scan where you can see inside of the cell non-destructively, so you don't have to cut the cell open," says Carolyn Larabell, a cell biologist at UC San Francisco.

Chronic lymphocytic leukemia (CLL) is a slow-growing cancer that affects white blood cells. Survival rates tend ... Experts don’t exactly know what causes CLL. However, there are risk factors ...

According to Autolus, this fast-off scheme closely mirrors the physiological interactions of T cells with their corresponding receptors. Results from a Phase Ib/II study of obe-cel in B-cell acute ...

Get Instant Summarized Text (Gist) Machine learning can predict gene mutations in acute myeloid leukemia (AML) cells by analyzing bone marrow images, potentially guiding treatment options. An AI ...

To overcome this, researchers used human T-cells and leukemia cells in specialized mouse models to develop ALA-CART, which showed promising results against acute lymphocytic leukemia (ALL) that had ...

The work addresses the role of translation initiation in the early induction of specific genes during T cell activation. It primarily uses the Jurkat T cell line and demonstrates that the translation ...