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California Institute for Regenerative Medicine2h
DISC5 Awards
The DISC5 Awards will support exploratory and innovative foundational research led by pairs of interdisciplinary investigators applying a range of technologies and approaches to address fundamental ...
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Alpha Clinics Network – CIRM
250+ Clinical Trials: Hosted at Alpha Clinics for CIRM funded and other research. 2000+ Patients Enrolled: Pioneers who participated in a clinical trial at an Alpha Clinic. 40+ Diseases & Conditions: ...
cirm.ca.gov6d
Shared Labs – CIRM
CIRM is supporting a network of 11 Shared Resources Laboratories (SRLs) for Stem Cell-Based Modeling, an important component of CIRM’s Infrastructure Program designed to address challenges that hinder ...
cirm.ca.gov6d
Manufacturing Network – CIRM
The California Cell and Gene Therapy Manufacturing Network was established by CIRM to expand the manufacturing capabilities necessary to bring stem cell and gene therapies from foundational research ...
cirm.ca.gov6d
CIRM Information for Applicants:
CIRM Disclaimer: The information in the table has been collected by CIRM to help CIRM awardees accelerate the development of pluripotent stem cell-derived therapeutics. The information is intended to ...
cirm.ca.gov5d
Explorando los mecanismos de las células madre – CIRM
Objetivo de la investigación Un nuevo tipo de APC sirve a los pacientes mayores como 1) mejor MSC en inmunomodulación (reducción de la inflamación) para el trasplante autólogo; 2) mejor fuente de ...
cirm.ca.gov6d
人类和小鼠组织工程结肠表现出多种神经元亚型，当供体结肠是无神经节细胞时，可以由肠神经系统祖细胞填充。 – CIRM
目的：组织工程结肠（TEC）有可能取代缺失或受损的大肠，但关键组成部分肠神经系统（ENS）尚未得到研究。 在各种肠神经病中，TEC 源自无神经节供体结肠，所得构建体也可能是无神经节的，从而限制了组织工程在先天性巨结肠病 (HD) 等疾病中的应用。 我们假设 TEC 可能包含多种肠道神经元亚型 ...
cirm.ca.gov21d
June 26 ICOC Meeting – CIRM
MEETING NOTICE AND AGENDA REGULAR MEETING OF THE INDEPENDENT CITIZENS OVERSIGHT COMMITTEE CALIFORNIA INSTITUTE FOR REGENERATIVE MEDICINE Organized Pursuant To The CALIFORNIA STEM CELL RESEARCH, ...
cirm.ca.gov20d
Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. – CIRM
Traumatic brain injuries (TBI) are the seventh leading cause of disability globally with 48.99 million prevalent cases and 7.08 million years lived with diability. Approximately 80 % of TBI patients ...
cirm.ca.gov18d
胚胎干细胞 – CIRM
该项目增强了干细胞的可及性、可扩展性和协作性。它提供了特征化的 hPSC 系、CRISPR 编辑和自动化平台上的分化，从而加速了生物学、疾病研究和再生医学的进展。… 继续阅读 干细胞建模的模块化自动化方法可提高通量、再现性和可及性 ...
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胚胎干细胞来源的胸腺上皮细胞 – CIRM
许多免疫缺陷是由于胸腺功能丧失所致，胸腺是 T 淋巴细胞的来源，T 淋巴细胞是免疫系统保护我们的身体免受感染所需的白细胞。胸腺上皮细胞 (TEC) 是皮肤样细胞胸腺中允许人体产生 T 淋巴细胞、TEC 的细胞会因癌症化疗和放射、HIV 感染和衰老而受损，导致免疫功能丧失。 在 CIRM 的资助下，我们 ...
cirm.ca.gov18d
胚胎干细胞自我更新途径汇聚于转录因子 Tfcp2l1。 – CIRM
胚胎干细胞可以在培养物中无限期地自我更新，同时保留分化成体内任何类型细胞的能力。 然而，人们对胚胎干细胞如何维持自我更新仍知之甚少。 在这里，我们揭示了Tfcp2l1在维持胚胎干细胞自我更新中的重要作用。 Tfcp2l1 是一种转录因子或蛋白质，控制细胞中哪些基因打开和关闭。 Tfcp2l1 表达的 ...